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Restoring airway integrity in cystic fibrosis patients

Cystic fibrosis is a rare genetic disease which can cause very serious symptoms. In particular, patients suffer from chronic bacterial infections that can lead to respiratory failure. It is caused by mutations in the CFTR ...

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IQ lower for survivors of PICU respiratory failure hospitalization

Survival of pediatric intensive care unit (PICU) hospitalization for respiratory failure is associated with a reduction in IQ scores relative to matched biological siblings, according to a study published in the March 1 issue ...

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The termrespiratory failure, in medicine, is used to describe inadequate gas exchange by the respiratory system, with the result that arterial oxygen and/or carbon dioxide levels cannot be maintained within their normal ranges. A drop in blood oxygenation is known as hypoxemia; a rise in arterial carbon dioxide levels is called hypercapnia. The normal reference values are: oxygen PaO2 greater than 80 mmHg (11 kPa), and carbon dioxide PaCO2 less than 45 mmHg (6.0 kPa). Classification into type I or type II relates to the absence or presence of hypercapnia respectively.

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